Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development ...

For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like ...

Analysis of scRNA-seq data from primate embryoid bodies highlights the value of cross-species comparisons for identifying and characterizing cell types, as marker genes can evolve fast.

When stem cells are injected into thick tissues, they often clump together and die from lack of oxygen or nutrients, making it almost impossible to use them for thick, highly vascularized tissues like ...

Microplastics that break off polystyrene food containers might prevent immune cells from fighting infections and clearing away dead cells, as well as reducing sperm counts, a mouse study hints. When ...

How can I heal faster? After an injury, surgery, persistent inflammation, or even an outbreak of acne, cell regeneration starts and the body goes into repair mode. It’s a complex, energy-intensive ...

The discovery of a gene essential to early embryonic development sheds light on the preliminary stages of human placenta formation. A team led by scientists from the University of California San Diego ...

Mouse embryonic stem cells (ESCs) have emerged as ideal tools for developmental biology research due to their characteristics such as unlimited proliferation and pluripotent differentiation potential.

Most people have heard of stem cells. They are often described as “miracle” cells –ones that can grow into any other type of cell in our bodies, promising revolutionary medical treatments. However, ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

Although embryonic stem cells (ESCs) have been successfully derived from mice and rats, efforts to establish chimeric and germline-competent ESC lines in species beyond rodents have been unsuccessful.