Early in the drug discovery process, it is necessary to begin studies on enantiomerically pure compounds due to the potential for unique efficacy and adverse effects associated with one enantiomer ...

Tokyo, Japan – Researchers from Tokyo Metropolitan University have created a new superconductor with a chiral crystalline structure by mixing two materials, one with superconductivity but no chirality ...

Atropisomers are a class of stereoisomers (chemical compounds that differ in spatial arrangement of atoms) arising from restricted rotation around a single bond and have various applications in ...

The separation of enantiomers – mirror-image forms of chiral compounds – is a pivotal process in chemical research due to its wide-reaching applications in pharmaceuticals, agrochemicals and materials ...

Like carbon and silicon, germanium’s lighter brethren on the periodic table, the metalloid can bond to four different groups, forming a chiral, tetrahedral molecule. Researchers at Nankai University ...

This module has been designed to introduce second-year organic chemistry students to the concepts of stereochemistry through the lens of the World Health Organization’s Model List of Essential ...

Many pharmaceuticals need to be a certain shape to fit into the binding pocket of the enzyme they target. Synthesizing molecules with the desired chirality requires controlled addition of functional ...

Modern chiral stationary phases allow rapid ER analysis and are applied to separate a wide range of chiral compounds. ER determination via chiral stationary phases allows facile assignment of absolute ...

Researchers have designed and built a new chemical tool inspired by natural metal-containing enzymes in living organisms. The product, a tetrahedral 'chiral zinc', maintains its shape for years, ...